Nephron COVID-19 Experience in Hemodialysis Patients: A Cue for Therapeutic Heparin-Based Strategies?

[tetano]

Nephron


. 2020 Jun 11;1-3.
doi: 10.1159/000508638. Online ahead of print.
COVID-19 Experience in Hemodialysis Patients: A Cue for Therapeutic Heparin-Based Strategies?


Antonio Pisani ¹ , Manuela Rizzo ² , Valentina Angelucci ² , Eleonora Riccio ³



Affiliations

• PMID: 32526763
• DOI: 10.1159/000508638

Abstract

In our opinion, the use of heparin could play a crucial role in these patients. In fact, recent studies have shown that heparin, the most commonly used anticoagulant during HD procedures, had anti-inflammatory properties and a direct antiviral action, due to its ability to prevent SARS-CoV-2 pseudovirus entry into host cells. These activities, together with its anticoagulant action, could explain the ability of heparin to ameliorate COVID-19 clinical course.

Keywords: Coronavirus disease 2019; Hemodialysis; Heparin.