Acta Paediatr Efficacy, Safety and Cost-Effectiveness of Hydroxychloroquine in Children With COVID-19: A Call for Evidence

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Acta Paediatr


. 2020 May 21.
doi: 10.1111/apa.15373. Online ahead of print.
Efficacy, Safety and Cost-Effectiveness of Hydroxychloroquine in Children With COVID-19: A Call for Evidence


Carlos E Rodr?guez-Mart?nez ^{1 2} , Ricardo M Fernandes ^{3 4} , Daniel B Hawcutt ^{5 6} , Ian P Sinha ⁷ , Rafael Leite Pacheco ⁸



Affiliations

• PMID: 32438459
• DOI: 10.1111/apa.15373

Abstract

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a serious threat to public health and local economies around the globe. This has created an urgent need to identify effective medications for its prevention and treatment (1). Among these treatments, the off-label use of hydroxychloroquine (HCQ), a less toxic derivate of chloroquine, has become a common practice among clinicians, including pediatricians, despite lack of evidence of its clinical efficacy for this indication (especially for pediatric patients) at present time (2).