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Clin Transl Sci. 2020 May 13. doi: 10.1111/cts.12815. [Epub ahead of print]
What do we know about remdesivir drug interactions?
Yang K1.
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Abstract
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-Co-V-2) has resulted in a critical need to rapidly develop new pharmacologic interventions and disseminate information. This has led to confusing and conflicting information on drug efficacy. Remdesivir has emerged as a promising treatment for SARS-Co-V-2 infection yet published clinical pharmacology and drug interaction studies are limited. Additional studies of the disposition of remdesivir, its active metabolite (GS-441524), and its triphosphate metabolite (GS-443902) are needed.
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PMID:32402130DOI:10.1111/cts.12815