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Minerva Med. Hyper-immune/convalescent plasma: an old option and a valid strategy for treatment of COVID-19?

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    Minerva Med. Hyper-immune/convalescent plasma: an old option and a valid strategy for treatment of COVID-19?


    Minerva Med. 2020 May 14. doi: 10.23736/S0026-4806.20.06616-1. [Epub ahead of print]
    Hyper-immune/convalescent plasma: an old option and a valid strategy for treatment of COVID-19?


    Saverino D1,2.

    Author information




    Abstract

    Currently, there are no approved specific antiviral agents for novel coronavirus disease (COVID-19). Hyper-immune/convalescent plasma derived from recently recovered donors seems to be useful to treat COVID-19 patients, an addition to maximal supportive care and antiviral agents. The endpoints are the improvement of clinical symptoms and laboratory parameters of these patients. However, the efficacy of hyper-immune/convalescent plasma treatment for severe infectious diseases is still controversial. The optimal dose and time point, as well as the clinical benefit of hyper- immune/convalescent plasma therapy, needs further investigation in larger well-controlled trials.



    PMID:32407051DOI:10.23736/S0026-4806.20.06616-1

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