Am J Trop Med Hyg. 2020 May 7. doi: 10.4269/ajtmh.20-0376. [Epub ahead of print]
Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine.
Asli R1, Abdullah MS2,1, Chong PL1, Metussin D1, Momin RN1, Mani BI3, Chong VH1,3,2.
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Abstract
Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe adult respiratory syndrome-coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use.
PMID:32383430DOI:10.4269/ajtmh.20-0376