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J Med Virol. What could be the better choice between ACE inhibitors and AT1R antagonists in coronavirus disease 2019 (COVID-19) patients?
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J Med Virol. What could be the better choice between ACE inhibitors and AT1R antagonists in coronavirus disease 2019 (COVID-19) patients?
J Med Virol. 2020 May 5. doi: 10.1002/jmv.25974. [Epub ahead of print]
What could be the better choice between ACE inhibitors and AT1R antagonists in coronavirus disease 2019 (COVID-19) patients?
Froldi G1.
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Abstract
Angiotensin-converting enzyme 2 (ACE2) removes a single residue from Ang I to yield Ang (1-9) and cleaves a single residue from Ang II to generate Ang (1-7). Thus ACE2 counterbalances ACE function decreasing Ang II levels1 . Consequently, this enzyme has a protective role against excessively high blood pressure values and high level of renin-angiotensin system (RAS) activation2 . This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
PMID:32369211DOI:10.1002/jmv.25974
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