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Pediatr Infect Dis J . PLASMAPHERESIS FOR RESCUE IN SEVERE ENCEPHALOPATHY AND MULTIORGAN FAILURE FROM FULMINANT INFLUENZA (H3N2) INFECTION
Pediatr Infect Dis J . PLASMAPHERESIS FOR RESCUE IN SEVERE ENCEPHALOPATHY AND MULTIORGAN FAILURE FROM FULMINANT INFLUENZA (H3N2) INFECTION
Pediatr Infect Dis J
. 2020 Sep 7.
doi: 10.1097/INF.0000000000002892. Online ahead of print. PLASMAPHERESIS FOR RESCUE IN SEVERE ENCEPHALOPATHY AND MULTIORGAN FAILURE FROM FULMINANT INFLUENZA (H3N2) INFECTION
We are presenting a case of 4-years-old previously healthy male with coma, severe acute hepatitis and multiorgan failure in presence of Influenza infection. Literature review highlighted an immune-mediated pathophysiology for such presentations so the child underwent a trial of plasmapheresis which resulted in a rapid clinical improvement and child was discharge in his baseline neurological status by day 14.