Multi-dimensional mining and analysis of core prescriptions in launched Chinese patent medicine for treatment of influenza

[tetano]

Zhongguo Zhong Yao Za Zhi. 2019 Nov;44(21):4738-4744. doi: 10.19540/j.cnki.cjcmm.20190812.501. [Multi-dimensional mining and analysis of core prescriptions in launched Chinese patent medicine for treatment of influenza].

[Article in Chinese]

Gu H¹, He WJ², Wei PL¹, Dang HX³, You RL¹, Liu J¹, Wang Z¹.
Author information

1 Institution of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700,China. 2 Xinjiang Medical University Urumqi 830011,China. 3 China Academy of Chinese Medical Sciences Beijing 100700,China.

Abstract

Through the multi-dimensional mining and analysis of launched anti-influenza proprietary Chinese medicines,this paper explores the study of the prescriptions and pharmacodynamics of traditional Chinese medicines for influenza. We established a standardized database by collecting and excavating the launched Chinese patent medicines that clearly describe the treatment of influenza. Frequency analysis and association rules were used to analyze the frequency of Chinese patent medicines for the treatment of influenza in the aspects of dosage form,category and prescription drugs. The network module partitioning method was used to excavate the core drug combination for influenza. The relationship between functional nouns was used to construct a network of functional terminology and analyze the relationship between its main functions. The pharmacological characteristics quantitative method was used to analyze the pharmacological characteristics of three heat-clearing and detoxifying type Chinese patent medicines for influenza. This article shows the traditional Chinese medicine syndrome differentiation ideas and medication rules for influenza treatment in many aspects and from multiple perspectives,so as to provide a certain reference for the clinical application of proprietary Chinese medicines for influenza and the development of new influenza drugs.


KEYWORDS:

core prescription; efficacy drug analysis; influenza; listed Chinese patent medicine; network module division

PMID: 31872672 DOI: 10.19540/j.cnki.cjcmm.20190812.501