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Therapie. 2017 Feb 17. pii: S0040-5957(17)30035-5. doi: 10.1016/j.therap.2016.12.011. [Epub ahead of print]
[Effectiveness of preventive treatment by Influenzinum in the winter period against the onset of influenza-like illnesses].
[Article in French]
Marinone C1, Bastard M1, Bonnet PA1, Gentile G1, Casanova L2.
Author information
Abstract
AIM:
In vitro Influenzinum induce a cellular change. We present the results of the first study examining the effectiveness of Influenzinum against influenza-like illnesses.
METHOD:
Retrospective cohort study during winter 2014-2015. After influenza epidemic, a self-assessment questionnaire was offered to patients presenting for a consultation. The primary endpoint was the declaration of an influenza-like illness. The exposed patients (treated by Influenzinum) were matched to two non-exposed patients (untreated) with a propensity score. A conditional logistic model expressed influenza-like illness risk reduction provided by the Influenzinum.
RESULTS:
The cohort included 3514 patients recruited from 46 general practitioners. After matching, the treated group (n=2041) and the untreated group (n=482) did not differ on variables collected. Influenzinum preventive therapy does not significantly alter the likelihood of influenza-like illness (adjusted odds ratio=0,91 [0,62 to 1,35], p=0,64).
CONCLUSION:
Influenzinum preventive therapy did not appear effective in preventing influenza-like illness.
Copyright ? 2017 Soci?t? fran?aise de pharmacologie et de th?rapeutique. Published by Elsevier Masson SAS. All rights reserved.
KEYWORDS:
Active immunization; Ambulatory care; Grippe humaine; Homeopathy; Hom?opathie; Human influenza; Influenzinum; M?decine ambulatoire; Propensity score; Score de propension; Vaccination
PMID: 28341159 DOI: 10.1016/j.therap.2016.12.011
[Effectiveness of preventive treatment by Influenzinum in the winter period against the onset of influenza-like illnesses].
[Article in French]
Marinone C1, Bastard M1, Bonnet PA1, Gentile G1, Casanova L2.
Author information
Abstract
AIM:
In vitro Influenzinum induce a cellular change. We present the results of the first study examining the effectiveness of Influenzinum against influenza-like illnesses.
METHOD:
Retrospective cohort study during winter 2014-2015. After influenza epidemic, a self-assessment questionnaire was offered to patients presenting for a consultation. The primary endpoint was the declaration of an influenza-like illness. The exposed patients (treated by Influenzinum) were matched to two non-exposed patients (untreated) with a propensity score. A conditional logistic model expressed influenza-like illness risk reduction provided by the Influenzinum.
RESULTS:
The cohort included 3514 patients recruited from 46 general practitioners. After matching, the treated group (n=2041) and the untreated group (n=482) did not differ on variables collected. Influenzinum preventive therapy does not significantly alter the likelihood of influenza-like illness (adjusted odds ratio=0,91 [0,62 to 1,35], p=0,64).
CONCLUSION:
Influenzinum preventive therapy did not appear effective in preventing influenza-like illness.
Copyright ? 2017 Soci?t? fran?aise de pharmacologie et de th?rapeutique. Published by Elsevier Masson SAS. All rights reserved.
KEYWORDS:
Active immunization; Ambulatory care; Grippe humaine; Homeopathy; Hom?opathie; Human influenza; Influenzinum; M?decine ambulatoire; Propensity score; Score de propension; Vaccination
PMID: 28341159 DOI: 10.1016/j.therap.2016.12.011