Phytochemistry. 2013 Oct 10. pii: S0031-9422(13)00386-5. doi: 10.1016/j.phytochem.2013.09.021. [Epub ahead of print]
Conjugates of a secoiridoid glucoside with a phenolic glucoside from the flower buds of Lonicera japonica Thunb.
Kashiwada Y, Omichi Y, Kurimoto SI, Shibata H, Miyake Y, Kirimoto T, Takaishi Y.
Source
Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan. Electronic address: kasiwada@tokushima-u.ac.jp.
Abstract
Secoiridoid glucosides, including two conjugates with a phenolic and two conjugates with a nicotinic acid derivative (3 and 4), together with seven known secoiridoid derivatives, were isolated from flower buds of Lonicera japonica. The structures were elucidated by spectroscopic analyses. Anti-influenza activities of six isolated compounds were also evaluated by plaque assay and neuraminidase inhibitory assay.
Copyright ? 2013 Elsevier Ltd. All rights reserved.
KEYWORDS:
Anti-influenza, Caprifoliaceae, Eugenol, Lonicera japonica, Nicotonic acid, Secoiridoid
PMID:
24120297
[PubMed - as supplied by publisher]
Conjugates of a secoiridoid glucoside with a phenolic glucoside from the flower buds of Lonicera japonica Thunb.
Kashiwada Y, Omichi Y, Kurimoto SI, Shibata H, Miyake Y, Kirimoto T, Takaishi Y.
Source
Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan. Electronic address: kasiwada@tokushima-u.ac.jp.
Abstract
Secoiridoid glucosides, including two conjugates with a phenolic and two conjugates with a nicotinic acid derivative (3 and 4), together with seven known secoiridoid derivatives, were isolated from flower buds of Lonicera japonica. The structures were elucidated by spectroscopic analyses. Anti-influenza activities of six isolated compounds were also evaluated by plaque assay and neuraminidase inhibitory assay.
Copyright ? 2013 Elsevier Ltd. All rights reserved.
KEYWORDS:
Anti-influenza, Caprifoliaceae, Eugenol, Lonicera japonica, Nicotonic acid, Secoiridoid
PMID:
24120297
[PubMed - as supplied by publisher]