MedComm (2020) . The determinants associated with zoonotic potential of influenza A viruses: BTN3A3 evasion mediated by residue mutation in the nucleoprotein

[tetano]

MedComm (2020)


. 2023 Dec 2;4(6):e441.
doi: 10.1002/mco2.441. eCollection 2023 Dec. The determinants associated with zoonotic potential of influenza A viruses: BTN3A3 evasion mediated by residue mutation in the nucleoprotein

Lili Tian ¹ , Maochen Li ¹ , Huahao Fan ¹



Affiliations

• PMID: 38045831
• PMCID: PMC10693302
• DOI: 10.1002/mco2.441

Free PMC article Abstract

Mutation of residue 313 in the viral nucleoprotein from F/L to Y/V (or substitutions to N, H, or Q in the nucleoprotein residue 52 adjacent to residue 313) facilitates IAVs to escape from BTN3A3 restriction on virus replication.