Tweet
Emerg Infect Dis
. 2021 Oct;27(10):2648-2657.
doi: 10.3201/eid2710.204765.
Burden of Influenza-Associated Respiratory Hospitalizations, Vietnam, 2014-2016
Nguyen Cong Khanh, Ashley L Fowlkes, Ngu Duy Nghia, Tran Nhu Duong, Ngo Huy Tu, Tran Anh Tu, Jeffrey W McFarland, Thoa Thi Minh Nguyen, Nga Thu Ha, Philip L Gould, Pham Ngoc Thanh, Nguyen Thi Huyen Trang, Vien Quang Mai, Phuc Nguyen Thi, Satoko Otsu, Eduardo Azziz-Baumgartner, Dang Duc Anh, A Danielle Iuliano
- PMID: 34545793
- DOI: 10.3201/eid2710.204765
Abstract
Influenza burden estimates are essential to informing prevention and control policies. To complement recent influenza vaccine production capacity in Vietnam, we used acute respiratory infection (ARI) hospitalization data, severe acute respiratory infection (SARI) surveillance data, and provincial population data from 4 provinces representing Vietnam's major regions during 2014-2016 to calculate provincial and national influenza-associated ARI and SARI hospitalization rates. We determined the proportion of ARI admissions meeting the World Health Organization SARI case definition through medical record review. The mean influenza-associated hospitalization rates per 100,000 population were 218 (95% uncertainty interval [UI] 197-238) for ARI and 134 (95% UI 119-149) for SARI. Influenza-associated SARI hospitalization rates per 100,000 population were highest among children <5 years of age (1,123; 95% UI 946-1,301) and adults >65 years of age (207; 95% UI 186-227), underscoring the need for prevention and control measures, such as vaccination, in these at-risk populations.
Keywords: Vietnam; burden; hospitalization; incidence; influenza; respiratory infections; vaccines; viruses.