Arch Virol . Severe Cases of Seasonal Influenza and Detection of Seasonal A(H1N2) in Russia in 2018-2019

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Arch Virol


. 2020 Jun 10.
doi: 10.1007/s00705-020-04699-z. Online ahead of print.
Severe Cases of Seasonal Influenza and Detection of Seasonal A(H1N2) in Russia in 2018-2019


Natalia P Kolosova ¹ , Tatyana N Ilyicheva ² , Alexey V Danilenko ² , Svetlana V Svyatchenko ² , Natalia I Goncharova ² , Julia A Bulanovich ² , Polina Yu Torzhkova ² , Alexander G Durymanov ² , Andrei S Gudymo ² , Alexander N Shvalov ² , Ivan M Susloparov ² , Tatyana V Tregubchak ² , Elena V Gavrilova ² , Rinat A Maksyutov ² , Alexander B Ryzhikov ²



Affiliations

• PMID: 32524262
• DOI: 10.1007/s00705-020-04699-z

Abstract

Data obtained from monitoring cases of severe influenza, cases of vaccinated individuals, and unique cases were used to describe influenza viruses that circulated in Russia in the 2018-2019 epidemic season. A high proportion of the mutations D222G/N in A(H1N1)pdm09 HA was detected in fatal cases. Viruses of the B/Victoria lineage with deletions in HA were detected in Russia, and a reassortant seasonal influenza A(H1N2) virus was identified. A C-terminal truncation in the NS1 protein was detected in a substantial proportion of A(H3N2) viruses.