Emerg Infect Dis. 2019 Oct;25(10):1973-1976. doi: 10.3201/eid2510.181931.
Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.
Pohlmann A, Hoffmann D, Grund C, Koethe S, H?ssy D, Meier SM, King J, Schink?the J, Ulrich R, Harder T, Beer M.
Abstract
We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.
KEYWORDS:
Germany; H5N5; H5N6; H5N8; H5Nx; HPAI; clade 2.3.4.4b; epizootic; ferret model; highly pathogenic avian influenza; influenza; reassortment; respiratory infections; viruses; zoonoses; zoonotic potential
PMID: 31538926 DOI: 10.3201/eid2510.181931
Free full text
Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.
Pohlmann A, Hoffmann D, Grund C, Koethe S, H?ssy D, Meier SM, King J, Schink?the J, Ulrich R, Harder T, Beer M.
Abstract
We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.
KEYWORDS:
Germany; H5N5; H5N6; H5N8; H5Nx; HPAI; clade 2.3.4.4b; epizootic; ferret model; highly pathogenic avian influenza; influenza; reassortment; respiratory infections; viruses; zoonoses; zoonotic potential
PMID: 31538926 DOI: 10.3201/eid2510.181931
Free full text