Virology. 2019 May 28;534:36-44. doi: 10.1016/j.virol.2019.05.011. [Epub ahead of print]
Detection of highly pathogenic avian influenza A(H5N6) viruses in waterfowl in Bangladesh.
Yang G1, Chowdury S2, Hodges E1, Rahman MZ2, Jang Y1, Hossain ME2, Jones J1, Stark TJ1, Di H1, Cook PW1, Ghosh S2, Azziz-Baumgartner E1, Barnes JR1, Wentworth DE1, Kennedy E3, Davis CT4.
Author information
Abstract
Bangladesh has reported repeated outbreaks of highly pathogenic avian influenza (HPAI) A(H5) viruses in poultry since 2007. Because of the large number of live poultry markets (LPM) relative to the population density of poultry throughout the country, these markets can serve as sentinel sites for HPAI A(H5) detection. Through active LPM surveillance during June 2016-June 2017, HPAI A(H5N6) viruses along with 14 other subtypes of influenza A viruses were detected. The HPAI A(H5N6) viruses belonged to clade 2.3.4.4 and were likely introduced into Bangladesh around March 2016. Human infections with influenza clade 2.3.4.4 viruses in Bangladesh have not been identified, but the viruses had several molecular markers associated with potential human infection. Vigilant surveillance at the animal-human interface is essential to identify emerging avian influenza viruses with the potential to threaten public and animal health.
Copyright ? 2019 Elsevier Inc. All rights reserved.
KEYWORDS:
A(H5N6); Highly pathogenic avian influenza virus; Live poultry market; Orthomyxovirus; Waterfowl
PMID: 31176062 DOI: 10.1016/j.virol.2019.05.011
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