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J Med Virol. 2018 Dec 17. doi: 10.1002/jmv.25363. [Epub ahead of print]
The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China.
Han L1, He W1, Yan H1, Li X1, Wang C2, Shi Q3, Zhou T4, Dong G1.
Author information
Abstract
To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin genes originate from JS/1/00-like sublineage, neuraminidase genes originate from BJ/94-like sublineage, PB1, PA, NP, and NS genes all come from SH/F/98-like sublineage, PB2 genes originate from ST/163/04-like sublineage, while M genes come from G1-like sublineage. Genotype analysis showed that our isolates were classified as genotype 57. Molecular analyses indicated that our strains contained specific sites characteristic of low-pathogenic viruses. The current study once again highlights the necessity for continued surveillance of novel H9N2 viruses.
KEYWORDS:
H9N2 influenza virus; genotype analysis; molecular analyses; phylogenetic analyses
PMID: 30560545 DOI: 10.1002/jmv.25363
The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China.
Han L1, He W1, Yan H1, Li X1, Wang C2, Shi Q3, Zhou T4, Dong G1.
Author information
Abstract
To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin genes originate from JS/1/00-like sublineage, neuraminidase genes originate from BJ/94-like sublineage, PB1, PA, NP, and NS genes all come from SH/F/98-like sublineage, PB2 genes originate from ST/163/04-like sublineage, while M genes come from G1-like sublineage. Genotype analysis showed that our isolates were classified as genotype 57. Molecular analyses indicated that our strains contained specific sites characteristic of low-pathogenic viruses. The current study once again highlights the necessity for continued surveillance of novel H9N2 viruses.
KEYWORDS:
H9N2 influenza virus; genotype analysis; molecular analyses; phylogenetic analyses
PMID: 30560545 DOI: 10.1002/jmv.25363