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Utility of state-level influenza disease burden and severity estimates to investigate an apparent increase in reported severe cases of influenza A(H1N1) pdm09 - Arizona, 2015-2016

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  • Utility of state-level influenza disease burden and severity estimates to investigate an apparent increase in reported severe cases of influenza A(H1N1) pdm09 - Arizona, 2015-2016

    Epidemiol Infect. 2018 Jun 14:1-7. doi: 10.1017/S0950268818001516. [Epub ahead of print]
    .

    Russell K1, Herrick K2, Venkat H1, Brady S2, Komatsu K2, Goodin K3, Berisha V3, Sunenshine R3, Perez-Velez C4, Elliott S5, Olsen SJ6, Reed C6.
    Author information

    Abstract

    The Arizona Department of Health Services identified unusually high levels of influenza activity and severe complications during the 2015-2016 influenza season leading to concerns about potential increased disease severity compared with prior seasons. We estimated state-level burden and severity to compare across three seasons using multiple data sources for community-level illness, hospitalisation and death. Severity ratios were calculated as the number of hospitalisations or deaths per community case. Community influenza-like illness rates, hospitalisation rates and mortality rates in 2015-2016 were higher than the previous two seasons. However, ratios of severe disease to community illness were similar. Arizona experienced overall increased disease burden in 2015-2016, but not increased severity compared with prior seasons. Timely estimates of state-specific burden and severity are potentially feasible and may provide important information during seemingly unusual influenza seasons or pandemic situations.


    KEYWORDS:

    Epidemiology; estimating disease prevalence; influenza; outbreaks; pandemic

    PMID: 29898797 DOI: 10.1017/S0950268818001516
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