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Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China

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  • Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China

    Arch Virol. 2018 Mar 20. doi: 10.1007/s00705-018-3818-6. [Epub ahead of print]
    Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China.

    Cao X1, Liu X2, Zheng S3, Xu L4, Wu H5, Liu J6.
    Author information

    Abstract

    Previous studies have shown that dogs are susceptible to influenza A viruses, and the close contact between dogs and humans poses a threat to public health. In 2015, a novel H3N8 influenza virus was isolated from a dog in eastern China. This strain was characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison and found to be most closely related to avian influenza viruses co-circulating in China. It was able to replicate in mice without prior adaptation. The continued circulation of this novel H3N8 influenza virus in dogs could endanger other mammalian species.


    PMID: 29556821 DOI: 10.1007/s00705-018-3818-6

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