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Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015-16

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  • Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015-16

    Oncotarget. 2017 Dec 22;9(5):6623-6629. doi: 10.18632/oncotarget.23601. eCollection 2018 Jan 19.
    Forty five percent of the Israeli population were infected with the influenza B Victoria virus during the winter season 2015-16.

    Sharabi S1,2, Bassal R3, Friedman N1,2, Drori Y1,2, Alter H1, Glatman-Freedman A2,3,4, Hindiyeh M1,2, Cohen D2, Mendelson E1,2, Shohat T2,3, Mandelboim M1,2.
    Author information

    Abstract

    While infection with influenza A viruses has been extensively investigated, infections with influenza B viruses which are commonly categorized into the highly homologous Victoria and Yamagata lineages, are less studied, despite their considerable virulence. Here we used RT-PCR assays, hemagglutination inhibition assays and antibody titers to determine the levels of influenza B infection. We report of high influenza B Victoria virus prevalence in the 2015-16 winter season in Israel, affecting approximately half of the Israeli population. We further show that the Victoria B virus infected individuals of all ages and that it was present in the country throughout the entire winter season. The vaccine however included the inappropriate Yamagata virus. We propose that a quadrivalent vaccine, that includes both Yamagata and Victoria lineages, should be considered for future influenza vaccination.


    KEYWORDS:

    Victoria; Yamagata; influenza B; vaccine

    PMID: 29464098 PMCID: PMC5814238 DOI: 10.18632/oncotarget.23601
    Free PMC Article
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