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Microbiol Insights. 2018 Feb 13;11:1178636118758651. doi: 10.1177/1178636118758651. eCollection 2018.
Viral and Bacterial Etiologies of Acute Respiratory Infections Among Children Under 5 Years in Senegal.
Assane D1, Makhtar C1, Abdoulaye D1, Amary F2, Djibril B3, Amadou D1, Niokhor DJB4, Amadou D5, Cheikh L6, Ndongo D2, Mbayame N2, Lamine F7, Bouh BCS1.
Author information
Abstract
Acute respiratory infections (ARIs) are the leading cause of infectious disease-related morbidity, hospitalization, and morbidity among children worldwide. This study aimed to assess the viral and bacterial causes of ARI morbidity and mortality in children under 5 years in Senegal. Nasopharyngeal samples were collected from children under 5 years who had ARI. Viruses and bacteria were identified using multiplex real-time reverse transcription-polymerase chain reaction and conventional biochemical techniques, respectively. Adenovirus was the most prevalent virus (50%; n = 81), followed by influenza virus (45.68%, n = 74), rhinovirus (40.12%; n = 65), enterovirus (25.31%; n = 41), and respiratory syncytial virus (16.05%; n = 26), whereas Streptococcus pneumoniae (17%; n = 29), Moraxella catarrhalis (15.43%; n = 25), and Haemophilus influenzae (8.02%; n = 13) were the most commonly isolated bacteria. Virus pathogens seem more likely to be more prevalent in our settings and were often associated with bacteria and S. pneumoniae (6%; 16) coinfection.
KEYWORDS:
Acute respiratory tract infections; bacteria; children <5 years; virus
PMID: 29467579 PMCID: PMC5815418 DOI: 10.1177/1178636118758651
Viral and Bacterial Etiologies of Acute Respiratory Infections Among Children Under 5 Years in Senegal.
Assane D1, Makhtar C1, Abdoulaye D1, Amary F2, Djibril B3, Amadou D1, Niokhor DJB4, Amadou D5, Cheikh L6, Ndongo D2, Mbayame N2, Lamine F7, Bouh BCS1.
Author information
Abstract
Acute respiratory infections (ARIs) are the leading cause of infectious disease-related morbidity, hospitalization, and morbidity among children worldwide. This study aimed to assess the viral and bacterial causes of ARI morbidity and mortality in children under 5 years in Senegal. Nasopharyngeal samples were collected from children under 5 years who had ARI. Viruses and bacteria were identified using multiplex real-time reverse transcription-polymerase chain reaction and conventional biochemical techniques, respectively. Adenovirus was the most prevalent virus (50%; n = 81), followed by influenza virus (45.68%, n = 74), rhinovirus (40.12%; n = 65), enterovirus (25.31%; n = 41), and respiratory syncytial virus (16.05%; n = 26), whereas Streptococcus pneumoniae (17%; n = 29), Moraxella catarrhalis (15.43%; n = 25), and Haemophilus influenzae (8.02%; n = 13) were the most commonly isolated bacteria. Virus pathogens seem more likely to be more prevalent in our settings and were often associated with bacteria and S. pneumoniae (6%; 16) coinfection.
KEYWORDS:
Acute respiratory tract infections; bacteria; children <5 years; virus
PMID: 29467579 PMCID: PMC5815418 DOI: 10.1177/1178636118758651