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J Infect. 2017 Aug 10. pii: S0163-4453(17)30259-1. doi: 10.1016/j.jinf.2017.08.002. [Epub ahead of print]
Early seasonal influenza vaccination and delayed influenza peaks - a possible cause of end-of-season outbreaks.
Tang JW1, Mutuyimana J2, Teo KW3, Lea S3, Galiano M4, Lackenby A4, Donaghy B3, Blount J5, Ellis J4, Range S3.
Author information
Abstract
Intra-seasonal waning of influenza vaccine-induced immunity is now well-recognised. This phenomenon may lead to end-of-season influenza outbreaks despite a good antigenic match with the seasonal influenza vaccine. Influenza immunisation later in the season may reduce such outbreaks if late seasonal influenza incidence is regular and predictable for a given population.
Copyright ? 2017. Published by Elsevier Ltd.
KEYWORDS:
immunity; incidence; influenza; late; seasonal; vaccine; waning
PMID: 28804025 DOI: 10.1016/j.jinf.2017.08.002
Early seasonal influenza vaccination and delayed influenza peaks - a possible cause of end-of-season outbreaks.
Tang JW1, Mutuyimana J2, Teo KW3, Lea S3, Galiano M4, Lackenby A4, Donaghy B3, Blount J5, Ellis J4, Range S3.
Author information
Abstract
Intra-seasonal waning of influenza vaccine-induced immunity is now well-recognised. This phenomenon may lead to end-of-season influenza outbreaks despite a good antigenic match with the seasonal influenza vaccine. Influenza immunisation later in the season may reduce such outbreaks if late seasonal influenza incidence is regular and predictable for a given population.
Copyright ? 2017. Published by Elsevier Ltd.
KEYWORDS:
immunity; incidence; influenza; late; seasonal; vaccine; waning
PMID: 28804025 DOI: 10.1016/j.jinf.2017.08.002