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US Healthcare Costs Attributable to Type A and Type B Influenza

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  • US Healthcare Costs Attributable to Type A and Type B Influenza

    Hum Vaccin Immunother. 2017 Jul 12:0. doi: 10.1080/21645515.2017.1345400. [Epub ahead of print]
    US Healthcare Costs Attributable to Type A and Type B Influenza.

    Yan S1, Weycker D2, Sokolowski S2.
    Author information


    While the overall healthcare burden of seasonal influenza in the United States (US) has been well characterized, the proportion of influenza burden attributable to type A and type B illness warrants further elucidation. The aim of this study was to estimate numbers of healthcare encounters and healthcare costs attributable to influenza viral strains A and B in the US during the 2001/2002 - 2008/2009 seasons. Healthcare encounters and costs in the US during the 2001/2002 - 2008/2009 seasons for influenza type A and influenza type B were estimated separately and collectively, by season and age group, based on data from published literature and secondary sources for: rates of influenza-related encounters requiring formal healthcare, unit costs of influenza-related healthcare encounters, and estimates of population size. Across eight seasons, projected annual numbers of influenza-related healthcare encounters ranged from 11.3-25.6 million, and healthcare costs, from $2.0-$5.8 billion. While the majority of influenza illness was attributable to type A strains, type B strains accounted for 37% of healthcare costs across all seasons, and as much as 66% in a single season. The outpatient burden of type B disease was considerable among persons aged 18-64 years while the hospital cost burden was highest in young children. Influenza viral strain B was associated with considerable health system burden each year during the period of interest. Increasing influenza vaccine coverage, especially with the recently approved quadrivalent products including an additional type B strain, could potentially reduce overall annual influenza burden in the US.


    Burden; Healthcare Costs; Influenza; Influenza A Virus; Influenza B Virus; Vaccine

    PMID: 28700268 DOI: 10.1080/21645515.2017.1345400