Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius - FluTrackers News and Information

Do not take medical advice from the internet. If you have any medical questions please consult your medical practitioner.

LATEST POSTS - click HERE

Check out the FAQ,Terms of Service & Disclaimers by clicking the link. Please register to be able to post. By viewing this site you are agreeing to our Terms of Service and Acknowledge our Disclaimers.

FluTrackers.com Inc. does not provide medical advice. Information on this web site is collected from various internet resources, and the FluTrackers board of directors makes no warranty to the safety, efficacy, correctness or completeness of the information posted on this site by any author or poster. The information collated here is for instructional and/or discussion purposes only and is NOT intended to diagnose or treat any disease, illness, or other medical condition. Every individual reader or poster should seek advice from their personal physician/healthcare practitioner before considering or using any interventions that are discussed on this website. By continuing to access this website you agree to consult your personal physican before using any interventions posted on this website, and you agree to hold harmless FluTrackers.com Inc., the board of directors, the members, and all authors and posters for any effects from use of any medication, supplement, vitamin or other substance, device, intervention, etc. mentioned in posts on this website, or other internet venues referenced in posts on this website.

We are not asking for any donations. Do not donate to any entity who says they are raising funds for us.

Announcement

Collapse

No announcement yet.

Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius

Collapse

X

Collapse

Posts

Latest Activity

Photos

Page of 1

Filter

Time

All Time Today Last Week Last Month

Show

All Discussions only Photos only Videos only Links only Polls only Events only

Filtered by:

Clear All

new posts

Previous template Next

tetano

Editor, Senior Moderator

Join Date: Dec 2009

Posts: 100353

Share

Tweet

#1

Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius

July 23, 2016, 04:03 AM

Mycobiology. 2016 Jun;44(2):117-20. doi: 10.5941/MYCO.2016.44.2.117. Epub 2016 Jun 30.
Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius.

Kim JY¹, Kim DW¹, Hwang BS¹, Woo EE¹, Lee YJ¹, Jeong KW¹, Lee IK¹, Yun BS¹.
Author information

Abstract

During our ongoing investigation of neuraminidase inhibitors from medicinal fungi, we found that the fruiting bodies of Phellinus igniarius exhibited significant inhibitory activity against neuraminidase from recombinant H3N2 influenza viruses. Two active compounds were isolated from the methanolic extract of P. igniarius through solvent partitioning and Sephadex LH-20 column chromatography. The active compounds were identified as phelligridins E and G on proton nuclear magnetic resonance ((1)H NMR) and electrospray ionization mass measurements. These compounds inhibited neuraminidases from recombinant rvH1N1, H3N2, and H5N1 influenza viruses, with IC50 values in the range of 0.7~8.1 ?M.

KEYWORDS:

Neuraminidase inhibitor; Phelligridin E; Phelligridin G; Phellinus igniarius

PMID: 27433123 PMCID: PMC4945539 DOI: 10.5941/MYCO.2016.44.2.117
[PubMed] Free PMC Article

Tags: None

Previous template Next

Help

Contact Us

Go to top

Powered by vBulletin® Version 5.7.5
Copyright © 2024 MH Sub I, LLC dba vBulletin. All rights reserved.

All times are GMT-5. This page was generated at 03:26 AM.

Working...

X