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Influenza 2014-2015 among pregnant Japanese women: primiparous vs multiparous women

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  • Influenza 2014-2015 among pregnant Japanese women: primiparous vs multiparous women

    Eur J Clin Microbiol Infect Dis. 2016 Feb 10. [Epub ahead of print]
    Influenza 2014-2015 among pregnant Japanese women: primiparous vs multiparous women.

    Yamada T1, Kawakami S2, Yoshida Y2, Kawamura H3, Ohta S3, Abe K4, Hamada H4, Dohi S5, Ichizuka K5, Takita H6, Baba Y7, Matsubara S7, Mochizuki J8, Unno N8, Maegawa Y9, Maeda M9, Inubashiri E10, Akutagawa N10, Kubo T11, Shirota T11, Oda Y12, Yamada T12, Yamagishi E13, Nakai A13, Fuchi N14, Masuzaki H14, Urabe S15, Kudo Y15, Nomizo M16, Sagawa N16, Maeda T17, Kamitomo M17, Kawabata K18, Kataoka S18, Shiozaki A19, Saito S19, Sekizawa A6, Minakami H20.
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    Abstract

    This study was performed to determine whether multiparous pregnant women are prone to influenza. A questionnaire survey was conducted at 19 centres located throughout Japan, targeting all 6,694 postpartum women within 7 days after birth before leaving the hospital. All women gave birth during the study period between March 1, 2015, and July 31, 2015. Data regarding vaccination and influenza infection in or after October 2014, age, previous experience of childbirth, and number and ages of cohabitants were collected. Seventy-eight percent (n = 51,97) of women given questionnaires responded. Of these, 2,661 (51 %) and 364 (7.0 %) women reported having been vaccinated and having contracted influenza respectively. Multiparous women had a higher risk of influenza regardless of vaccination status (8.9 % [121/1362] vs 5.7 % [74/1299], relative risk [95 % confidence interval], 1.80 [1.36 to 2.38] for vaccinated and 9.3 % [112/1198] vs 4.3 % [57/1328], 2.18 [1.60 to 2.97] for unvaccinated women) compared to primiparous women. The risk of influenza increased with increasing number of cohabitants: 4.8 % (100/2089), 7.5 %, (121/1618), 9.0 %, (71/785), and 10.4 % (58/557) for women with 1, 2, 3, and ≥4 cohabitants respectively. Family size is a risk factor for influenza infection in pregnancy.


    PMID: 26864040 [PubMed - as supplied by publisher]
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