Tweet
J Lab Autom. 2015 Apr 10. pii: 2211068215580935. [Epub ahead of print]
Biosensors for Monitoring Airborne Pathogens.
Fronczek CF1, Yoon JY2.
Author information
Abstract
Airborne pathogens affect both humans and animals and are often highly and rapidly transmittable. Many problematic airborne pathogens, both viral (influenza A/H1N1, Rubella, and avian influenza/H5N1) and bacterial (Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bacillus anthracis), have huge impacts on health care and agricultural applications, and can potentially be used as bioterrorism agents. Many different laboratory-based methods have been introduced and are currently being used. However, such detection is generally limited by sample collection, including nasal swabs and blood analysis. Direct identification from air (specifically, aerosol samples) would be ideal, but such detection has not been very successful due to the difficulty in sample collection and the extremely low pathogen concentration found in aerosol samples. In this review, we will discuss the portable biosensors and/or micro total analysis systems (?TAS) that can be used for monitoring such airborne pathogens, similar to smoke detectors. Current laboratory-based methods will be reviewed, and possible solutions to convert these lab-based methods into ?TAS biosensors will be discussed.
? 2015 Society for Laboratory Automation and Screening.
KEYWORDS:
Rubella; aerosol; anthrax; influenza; micro total analysis system; pneumonia; tuberculosis
PMID: 25862683 [PubMed - as supplied by publisher]
Biosensors for Monitoring Airborne Pathogens.
Fronczek CF1, Yoon JY2.
Author information
Abstract
Airborne pathogens affect both humans and animals and are often highly and rapidly transmittable. Many problematic airborne pathogens, both viral (influenza A/H1N1, Rubella, and avian influenza/H5N1) and bacterial (Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bacillus anthracis), have huge impacts on health care and agricultural applications, and can potentially be used as bioterrorism agents. Many different laboratory-based methods have been introduced and are currently being used. However, such detection is generally limited by sample collection, including nasal swabs and blood analysis. Direct identification from air (specifically, aerosol samples) would be ideal, but such detection has not been very successful due to the difficulty in sample collection and the extremely low pathogen concentration found in aerosol samples. In this review, we will discuss the portable biosensors and/or micro total analysis systems (?TAS) that can be used for monitoring such airborne pathogens, similar to smoke detectors. Current laboratory-based methods will be reviewed, and possible solutions to convert these lab-based methods into ?TAS biosensors will be discussed.
? 2015 Society for Laboratory Automation and Screening.
KEYWORDS:
Rubella; aerosol; anthrax; influenza; micro total analysis system; pneumonia; tuberculosis
PMID: 25862683 [PubMed - as supplied by publisher]