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PLoS ONE. Avian Influenza H9N2 Seroprevalence among Poultry Workers in Pune, India, 2010
[Source: PLoS ONE, full text: (LINK). Abstract, edited.]
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Avian Influenza H9N2 Seroprevalence among Poultry Workers in Pune, India, 2010
by Shailesh D. Pawar, Babasaheb V. Tandale, Chandrashekhar G. Raut, Saurabh S. Parkhi, Tanaji D. Barde, Yogesh K. Gurav, Sadhana S. Kode, Akhilesh C. Mishra
Avian influenza (AI) H9N2 has been reported from poultry in India. A seroepidemiological study was undertaken among poultry workers to understand the prevalence of antibodies against AI H9N2 in Pune, Maharashtra, India. A total of 338 poultry workers were sampled. Serum samples were tested for presence of antibodies against AI H9N2 virus by hemagglutination inhibition (HI) and microneutralization (MN) assays. A total of 249 baseline sera from general population from Pune were tested for antibodies against AI H9N2 and were negative by HI assay using ≥40 cut-off antibody titre. Overall 21 subjects (21/338 = 6.2%) were positive for antibodies against AI H9N2 by either HI or MN assays using ≥40 cut-off antibody titre. A total of 4.7% and 3.8% poultry workers were positive for antibodies against AI H9N2 by HI and MN assay respectively using 40 as cut-off antibody titre. This is the first report of seroprevalence of antibodies against AI H9N2 among poultry workers in India.
-by Shailesh D. Pawar, Babasaheb V. Tandale, Chandrashekhar G. Raut, Saurabh S. Parkhi, Tanaji D. Barde, Yogesh K. Gurav, Sadhana S. Kode, Akhilesh C. Mishra
Avian influenza (AI) H9N2 has been reported from poultry in India. A seroepidemiological study was undertaken among poultry workers to understand the prevalence of antibodies against AI H9N2 in Pune, Maharashtra, India. A total of 338 poultry workers were sampled. Serum samples were tested for presence of antibodies against AI H9N2 virus by hemagglutination inhibition (HI) and microneutralization (MN) assays. A total of 249 baseline sera from general population from Pune were tested for antibodies against AI H9N2 and were negative by HI assay using ≥40 cut-off antibody titre. Overall 21 subjects (21/338 = 6.2%) were positive for antibodies against AI H9N2 by either HI or MN assays using ≥40 cut-off antibody titre. A total of 4.7% and 3.8% poultry workers were positive for antibodies against AI H9N2 by HI and MN assay respectively using 40 as cut-off antibody titre. This is the first report of seroprevalence of antibodies against AI H9N2 among poultry workers in India.
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