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A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu

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  • A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu

    Influenza Other Respir Viruses. 2016 Jul 11. doi: 10.1111/irv.12406. [Epub ahead of print]
    A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu.

    Smith LE1, D'Antoni D2, Jain V1, Pearce JM3, Weinman J2, Rubin GJ1.
    Author information

    Abstract

    AIM:

    The aim of this study was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza.
    METHOD:

    Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence to antivirals.
    RESULTS:

    Twenty-six studies were included in the review; twenty identified through the literature search and six through other means. Of these studies, eighteen assessed predictors of actual adherence to antivirals whereas eight assessed predictors of intended adherence. The most commonly found predictor of and self-reported reason for non-adherence was the occurrence of side-effects. Other predictors include perceptions surrounding self-efficacy, response-efficacy and perceived personal consequences as well as social influences of others' experiences of taking antivirals.
    CONCLUSION:

    Predictors identified in this review can be used to help inform communications in order to increase adherence to antivirals in both seasonal and pandemic influenza. This article is protected by copyright. All rights reserved.
    This article is protected by copyright. All rights reserved.


    KEYWORDS:

    Adherence; antivirals; influenza; pandemic

    PMID: 27397480 DOI: 10.1111/irv.12406
    [PubMed - as supplied by publisher] Free full text
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