J Med Virol . Detect and suppress future zoonotic-derived outbreaks: A lesson from last two decades

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J Med Virol


. 2023 Jan 30.
doi: 10.1002/jmv.28530. Online ahead of print.
Detect and suppress future zoonotic-derived outbreaks: A lesson from last two decades


Nguyen Khoi Quan ¹ , Dang Huu Thien ¹ , Nguyen Tien Huy ²



Affiliations

• PMID: 36714988
• DOI: 10.1002/jmv.28530

Abstract

COVID-19 pandemic has revealed how vulnerable and inexperienced we are when dealing with an unprecedented global infectious threat. Looking back on the last few decades, there has been a surge in zoonotic-derived viruses globally. Notably, these outbreaks emerged as harmless zoonotic diseases within a favorable environment, then spilled over to humans and widely spread to become outbreaks. Most of these are respiratory viruses (particularly Orthomyxoviridae Orthomyxoviridae or Coronaviridae Coronaviridae family), with high transmissibility and can be easily spread. Low- and middle-income countries, particularly those with tropical climates, provide ideal environments for the growth and evolution of these zoonotic viruses. Nevertheless, a lot of our advanced centers for infectious diseases are located in high-income countries (HIC) and focus on human pathogens only (e.g., influenza, RSV, adenovirus). We should critically think about reallocating health resources in the near-term. It is an urge for a few surveillance centers aim to detect surges in cases of respiratory pathogens or any spikes in cases, and suppress the transmission chain from an early stage. In this article, we digest lessons learned from the previous spillover pandemics and suggest actionable tactics to deal with future pandemics properly. This article is protected by copyright. All rights reserved.

Keywords: Coronavirus.