J Clin Med . Hospital Resources May Be an Important Aspect of Mortality Rate among Critically Ill Patients with COVID-19: The Paradigm of Greece

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J Clin Med


. 2020 Nov 20;9(11):E3730.
doi: 10.3390/jcm9113730.
Hospital Resources May Be an Important Aspect of Mortality Rate among Critically Ill Patients with COVID-19: The Paradigm of Greece


Christina Routsi ¹ , Eleni Magira ¹ , Stelios Kokkoris ¹ , Ilias Siembos ¹ , Charikleia Vrettou ¹ , Dimitris Zervakis ¹ , Eleni Ischaki ¹ , Sotiris Malahias ¹ , Ioanna Sigala ¹ , Andreas Asimakos ¹ , Theodora Daidou ¹ , Panagiotis Kaltsas ¹ , Evangelia Douka ¹ , Adamandia Sotiriou ¹ , Vassiliki Markaki ¹ , Prodromos Temberikidis ¹ , Apostolos Koroneos ¹ , Panagiotis Politis ¹ , Zafiria Mastora ¹ , Efrosini Dima ¹ , Theodoros Tsoutsouras ¹ , Ioannis Papahatzakis ¹ , Panagiota Gioni ¹ , Athina Strilakou ¹ , Aikaterini Maragouti ¹ , Eleftheria Mizi ¹ , Ageliki Kanavou ¹ , Aikaterini Sarri ¹ , Evdokia Gavrielatou ¹ , Spyros Mentzelopoulos ¹ , Ioannis Kalomenidis ¹ , Vassilios Papastamopoulos ² , Anastasia Kotanidou ¹ , Spyros Zakynthinos ¹



Affiliations

• PMID: 33233686
• DOI: 10.3390/jcm9113730

Abstract

For critically ill patients with coronavirus disease 2019 (COVID-19) who require intensive care unit (ICU) admission, extremely high mortality rates (even 97%) have been reported. We hypothesized that overburdened hospital resources by the extent of the pandemic rather than the disease per se might play an important role on unfavorable prognosis. We sought to determine the outcome of such patients admitted to the general ICUs of a hospital with sufficient resources. We performed a prospective observational study of adult patients with COVID-19 consecutively admitted to COVID-designated ICUs at Evangelismos Hospital, Athens, Greece. Among 50 patients, ICU and hospital mortality was 32% (16/50). Median PaO₂/FiO₂ was 121 mmHg (interquartile range (IQR), 86-171 mmHg) and most patients had moderate or severe acute respiratory distress syndrome (ARDS). Hospital resources may be an important aspect of mortality rates, since severely ill COVID-19 patients with moderate and severe ARDS may have understandable mortality, provided that they are admitted to general ICUs without limitations on hospital resources.

Keywords: ARDS; COVID-19; SOFA; acute hypoxemic respiratory failure; acute respiratory distress syndrome; coronavirus; coronavirus disease 2019; critical care; mortality; sequential organ failure assessment.