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May 20 2022
ARTIC Network
Philippe Selhorst1 & Antonio Mauro Rezende1, Tessa de Block1, Sandra Coppens1, Hilde Smet1, Joachim Mariën2, Anne Hauner1, Isabel Brosius1, Laurens Liesenborghs1, Emmanuel Bottieau1, Eric Florence1, Eugene Bangwen1, Kevin K Ariën1,2, Marjan Van Esbroeck1, Chris Kenyon1, Koen Vercauteren1
Monkeypox virus (MPXV) is a zoonotic virus that circulates in a yet unidentified animal reservoir in Africa with humans and primates being considered incidental hosts. The virus belongs to the same genus as the variola virus, which causes smallpox, and presents with a similar presentation of a febrile prodrome and a characteristic rash. A case fatality rate of up to 10% in children has been reported, but is much lower in adults.
Although MPXV is usually constrained to small outbreaks in remote parts of Central and West African countries, with cases elsewhere mostly linked to Africa travel, several cases of monkeypox virus are recently and increasingly being detected around the world (United Kingdom, Portugal, Spain, Sweden, Italy, Canada, Belgium, Australia, France, Germany, and the USA). This raises concerns about increased human-to-human transmission and necessitates urgent investigation into the underlying causes.
Here we report the nearly full genome of a 30-yr old male case in Belgium with a travel history to Lisbon, Portugal who presented to the ITM STI clinic on May 13th with perianal papules and 1cm painful inguinal adenopathy bilaterally. ...
ARTIC Network
Philippe Selhorst1 & Antonio Mauro Rezende1, Tessa de Block1, Sandra Coppens1, Hilde Smet1, Joachim Mariën2, Anne Hauner1, Isabel Brosius1, Laurens Liesenborghs1, Emmanuel Bottieau1, Eric Florence1, Eugene Bangwen1, Kevin K Ariën1,2, Marjan Van Esbroeck1, Chris Kenyon1, Koen Vercauteren1
Monkeypox virus (MPXV) is a zoonotic virus that circulates in a yet unidentified animal reservoir in Africa with humans and primates being considered incidental hosts. The virus belongs to the same genus as the variola virus, which causes smallpox, and presents with a similar presentation of a febrile prodrome and a characteristic rash. A case fatality rate of up to 10% in children has been reported, but is much lower in adults.
Although MPXV is usually constrained to small outbreaks in remote parts of Central and West African countries, with cases elsewhere mostly linked to Africa travel, several cases of monkeypox virus are recently and increasingly being detected around the world (United Kingdom, Portugal, Spain, Sweden, Italy, Canada, Belgium, Australia, France, Germany, and the USA). This raises concerns about increased human-to-human transmission and necessitates urgent investigation into the underlying causes.
Here we report the nearly full genome of a 30-yr old male case in Belgium with a travel history to Lisbon, Portugal who presented to the ITM STI clinic on May 13th with perianal papules and 1cm painful inguinal adenopathy bilaterally. ...