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Am J Clin Dermatol . Cutaneous Manifestations of SARS-CoV-2 Infection

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  • Am J Clin Dermatol . Cutaneous Manifestations of SARS-CoV-2 Infection


    Am J Clin Dermatol


    . 2022 Mar 5.
    doi: 10.1007/s40257-022-00675-2. Online ahead of print.
    Cutaneous Manifestations of SARS-CoV-2 Infection


    Thy Huynh 1 2 , Xavier Sanchez-Flores 1 2 , Judy Yau 3 , Jennifer T Huang 4 5



    Affiliations

    Abstract

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic, affecting people worldwide. SARS-CoV-2 infection is a multisystem disease with potential for detrimental effects on various systemic organs. It affects people of all ages with varying degrees of disease severity. Patients with SARS-CoV-2 infection commonly present with dry cough, fever, and fatigue. A clinical spectrum of skin findings secondary to SARS-CoV-2 has also been reported. The most common cutaneous patterns associated with COVID-19 are chilblain-like lesions (CBLL), maculopapular lesions, urticarial lesions, vesicular lesions, and livedoid lesions. Other skin findings secondary to SARS-COV-2 infection are erythema multiforme (EM)-like lesions and skin findings associated with multisystem inflammatory syndrome in children (MIS-C) and rarely multisystem inflammatory syndrome in adults (MIS-A). Physician awareness of skin manifestations of SARS-CoV-2 infection can help with early identification and treatment. This narrative review provides an update of various skin manifestations reported with SARS-CoV-2 infection, including clinical presentation, proposed pathogenesis, histopathology, prognosis, and treatment options.


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