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Neurol Int . Guillain-Barré Syndrome in the COVID-19 Pandemic

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  • Neurol Int . Guillain-Barré Syndrome in the COVID-19 Pandemic


    Neurol Int


    . 2021 Dec 24;14(1):34-48.
    doi: 10.3390/neurolint14010003.
    Guillain-Barré Syndrome in the COVID-19 Pandemic


    Abdullah Ahmad Tawakul 1 , Amal Waleed Al-Doboke 2 , Shahad Ali Altayyar 2 , Seham Abdulhafith Alsulami 2 , Ahlam Musallam Alfahmi 2 , Raghad Turki Nooh 2



    Affiliations

    Abstract

    There have been several reported cases of severe acute respiratory syndrome (SARS-CoV-2) infection that were associated with an increased incidence of neurological manifestations, including Guillain-Barré syndrome (GBS). This review aims to present information on the reports of GBS associated with coronavirus disease 2019 (COVID-19) infection. Our review is retrospective work examining articles published from the 1 April 2020 to the 8 May 2021 in the English language. We used the diagnostic criteria and classification published by the National Institute of Neurological Disorders and Stroke and Brighton Collaboration. GBS is usually a postinfectious syndrome, but GBS in the COVID-19 pandemic also takes on a para-infectious profile. In the reports, the genetic factor has a role in developing GBS in some patients. In conclusion, the association between COVID-19 and GBS is not very clear. Still, one mechanism is strongly associated with COVID-19 and immune-mediated neurological complications, which is molecular mimicry between SARS-CoV-2 and human autoantigens.

    Keywords: COVID-19; GBS; Guillain–Barré syndrome; SARS; SARS-CoV-2.


  • #2

    Neurol Int


    . 2022 Jan 6;14(1):89.
    doi: 10.3390/neurolint14010007.
    COVID-19 Is Changing Our Understanding of the Neuroscience of Viral Infections: What We Can Do to Prepare for the Future?


    Kore Kai Liow 1 2 , Jason Viereck 1 2



    Affiliations

    Abstract

    In the approximately two years since the emergence of COVID-19 (Coronavirus Disease 2019) myriad neurological symptoms have been reported that are seemingly unrelated to each other [...].


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