Intern Med . A Case of Suspected Tuberculous Pleurisy and Coronavirus Disease 2019 Comorbidity

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Intern Med


. 2021 Dec 28.
doi: 10.2169/internalmedicine.6920-21. Online ahead of print.
A Case of Suspected Tuberculous Pleurisy and Coronavirus Disease 2019 Comorbidity


Yoh Yamaguchi ¹ , Masao Hashimoto ¹ , Susumu Saito ¹ , Tie Morita ¹ , Akinari Tsukada ¹ , Yusaku Kusaba ¹ , Takashi Katsuno ¹ , Manabu Suzuki ¹ , Jin Takasaki ¹ , Shinyu Izumi ¹ , Akihiro Matsunaga ² , Yukihito Ishizaka ² , Masayuki Hojo ¹ , Haruhito Sugiyama ¹



Affiliations

• PMID: 34980790
• DOI: 10.2169/internalmedicine.6920-21

Abstract

A 33-year-old woman with a fever, cough, and pharyngitis was admitted after left-sided pleural effusion was detected. The fever and upper respiratory symptoms were confirmed, and she was diagnosed with coronavirus disease (COVID-19) after showing a positive polymerase chain reaction (PCR) test. After thoracentesis, pleural fluid revealed elevated adenosine deaminase values and a positive QuantiFeron test; tuberculous pleurisy was thus suspected. Subsequent SARS-CoV-2 PCR and anti-SARS-CoV-2 Spike IgG tests were negative, suggesting that the initial PCR result had been erroneous. However, we were unable to confirm this. Data concerning COVID-19 diagnostics are insufficient at present. It is important to make comprehensive judgments regarding the diagnosis and treatment of patients as well as public health.

Keywords: COVID-19; SARS-CoV-2; tuberculous pleurisy.