J Obstet Gynaecol Can . Preeclampsia-like syndrome in a pregnant patient with Coronavirus Disease 2019 (COVID-19)

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J Obstet Gynaecol Can


. 2021 Oct 11;S1701-2163(21)00752-0.
doi: 10.1016/j.jogc.2021.09.015. Online ahead of print.
Preeclampsia-like syndrome in a pregnant patient with Coronavirus Disease 2019 (COVID-19)


Amir Naeh ¹ , Alexandra Berezowsky ² , Mark H Yudin ² , Irfan A Dhalla ³ , Howard Berger ²



Affiliations

• PMID: 34648956
• DOI: 10.1016/j.jogc.2021.09.015

Abstract

Background: Hypertension, proteinuria, and hepatic dysfunction have been described as manifestations of coronavirus disease 2019 (COVID-19) and are generally accepted as poor prognostic factors. However, these same findings can also occur in pregnant women with preeclampsia, thus creating a diagnostic challenge.
Case: We report a case of COVID-19 infection in an otherwise healthy pregnant patient with secondary hypertension, proteinuria, and significant hepatic dysfunction. Maternal placental growth factor (PlGF) testing was used to rule out preeclampsia. The patient received supportive care and improved significantly. She went on to have a spontaneous vaginal term delivery of a healthy male baby.
Conclusion: COVID-19 infection in pregnancy may present as preeclampsia-like syndrome. PlGF testing can be used to differentiate preeclampsia from COVID-19 and facilitate appropriate management.

Keywords: COVID-19; PLGF; preeclampsia; pregnancy outcome.