Circ J . Multiple Cardiovascular Diseases or Risk Factors Increase the Severity of Coronavirus Disease 2019

[tetano]

Circ J


. 2021 Sep 22.
doi: 10.1253/circj.CJ-21-0684. Online ahead of print.
Multiple Cardiovascular Diseases or Risk Factors Increase the Severity of Coronavirus Disease 2019


Tomoyuki Yamada ^{1 2} , Taku Ogawa ^{1 3} , Kenta Minami ¹ , Yusuke Kusaka ^{1 4} , Masaaki Hoshiga ⁵ , Akira Ukimura ^{1 5} , Takahide Sano ⁶ , Takeshi Kitai ⁷ , Taishi Yonetsu ⁸ , Sho Torii ⁹ , Shun Kohsaka ¹⁰ , Shunsuke Kuroda ¹¹ , Koichi Node ¹² , Yuya Matsue ^{13 14} , Shingo Matsumoto ¹⁵



Affiliations

• PMID: 34556591
• DOI: 10.1253/circj.CJ-21-0684

Abstract

Background: This study aimed to determine whether disease severity varied according to whether coronavirus disease 2019 (COVID-19) patients had multiple or single cardiovascular diseases and risk factors (CVDRFs).Methods and Results:COVID-19 patients with single (n=281) or multiple (n=412) CVDRFs were included retrospectively. Multivariable logistic regression showed no significant difference in the risk of in-hospital death between groups, but patients with multiple CVDRFs had a significantly higher risk of acute respiratory distress syndrome (odds ratio: 1.75, 95% confidence interval: 1.09-2.81).
Conclusions: COVID-19 patients with multiple CVDRFs have a higher risk of complications than those with a single CDVRF.

Keywords: Cardiovascular disease; Cardiovascular risk factors; Coronavirus disease.