Respirol Case Rep
. 2021 Jun 8;9(7):e00801.
doi: 10.1002/rcr2.801. eCollection 2021 Jul.
Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19
Saori Amiya 1 , Haruhiko Hirata 1 , Takayuki Shiroyama 1 , Yuichi Adachi 1 , Takayuki Niitsu 1 , Yoshimi Noda 1 , Takatoshi Enomoto 1 , Reina Hara 1 , Kiyoharu Fukushima 1 , Yasuhiko Suga 1 , Kotaro Miyake 1 , Moe Koide 2 , Akinori Uchiyama 2 , Yoshito Takeda 1 , Atsushi Kumanogoh 1
Affiliations
- PMID: 34136262
- PMCID: PMC8185623
- DOI: 10.1002/rcr2.801
Abstract
Coronavirus disease 2019 (COVID-19) can cause severe lymphopenia and respiratory failure requiring prolonged invasive mechanical ventilation (MV). COVID-19 patients with severe lymphopenia or respiratory failure are at risk of developing secondary infections. Here, we present the needle autopsy findings of a critically ill patient with COVID-19 who required reintubation and prolonged MV, and eventually died of secondary cytomegalovirus (CMV) pneumonia. This case highlights the potential risk of long-term steroid use and the need for routine monitoring for CMV infection in critically ill patients with COVID-19.
Keywords: COVID‐19; Co‐infection; corticosteroid therapy; cytomegalovirus pneumonia; lymphopenia.