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Histopathology . A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis

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  • Histopathology . A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis


    Histopathology


    . 2021 May 13.
    doi: 10.1111/his.14402. Online ahead of print.
    A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis


    Sasha Libbrecht 1 , Jolien Van Cleemput 2 , Linos Vandekerckhove 2 3 , Sofie Colman 4 , Elizaveta Padalko 4 , Bruno Verhasselt 4 , Koen Van de Vijver 1 , Am?lie Dendooven 1 , Isabelle Dehaene 5 , Jo Van Dorpe 1



    Affiliations

    Abstract

    From the start of the global COVID-19 pandemic, a lot of attention has been focused on how SARS-CoV-2 (severe acute respiratory syndrome coronavirus type 2) impacts pregnancy. The current evidence suggests that pregnant women may be at an increased risk for more severe COVID-19 disease and an increase in maternal death rate has been observed worldwide (1,2).

    Keywords: B.1.1.7; C4d; COVID-19; Histiocytic intervillositis; Placenta; SARS-CoV-2; Trophoblast necrosis; UK-variant.

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