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Transplant Proc
. 2021 Mar 12;S0041-1345(21)00150-0.
doi: 10.1016/j.transproceed.2021.03.007. Online ahead of print.
Post-Covid-19 Cholangiopathy-A New Indication for Liver Transplantation: A Case Report
Francisco A Durazo 1 , Allyssa A Nicholas 2 , Jennifer J Mahaffey 2 , Shannon Sova 3 , John J Evans 4 , Juan Pablo Trivella 5 , Veronica Loy 5 , Joohyun Kim 2 , Michael A Zimmerman 2 , Johnny C Hong 6
Affiliations
- PMID: 33846012
- DOI: 10.1016/j.transproceed.2021.03.007
Abstract
Liver injury is one of the nonpulmonary manifestations described in coronavirus disease 2019 (COVID-19). Post-COVID-19 cholangiopathy is a special entity of liver injury that has been suggested as a variant of secondary sclerosing cholangitis in critically ill patients (SSC-CIP). In the general population, the outcome of SSC-CIP has been reported to be poor without orthotopic liver transplantation (OLT). However, the role of OLT for post-COVID-19 cholangiopathy is unknown. We present a case report of a 47-year-old man who recovered from acute respiratory distress syndrome from COVID-19 and subsequently developed end-stage liver disease from post-COVID-19 cholangiopathy. The patient underwent OLT and is doing well with normal liver tests for 7 months. To our knowledge, this is the first case report of a patient who underwent successful liver transplantation for post-COVID-19 cholangiopathy.