Infect Drug Resist . Renal Involvement in COVID-19: A Review of the Literature

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Infect Drug Resist


. 2021 Mar 5;14:895-903.
doi: 10.2147/IDR.S288869. eCollection 2021.
Renal Involvement in COVID-19: A Review of the Literature


Marco Giuseppe Migliaccio ^{# 1} , Marco Di Mauro ^{# 1} , Riccardo Ricciolino ¹ , Giorgio Spiniello ¹ , Vincenzo Carfora ¹ , Nicoletta Verde ¹ , Filiberto Fausto Mottola ¹ , Nicola Coppola ² , Vanvitelli COVID-19 Group



Affiliations

• PMID: 33707958
• PMCID: PMC7943324
• DOI: 10.2147/IDR.S288869

Abstract

Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.

Keywords: COVID-19; SARS-CoV-2; acute kidney injury; kidney injury.