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Endocrinol Metab (Seoul) . Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study

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  • Endocrinol Metab (Seoul) . Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study


    Endocrinol Metab (Seoul)


    . 2021 Feb;36(1):196-200.
    doi: 10.3803/EnM.2020.856. Epub 2021 Feb 24.
    Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study


    Wonjun Ji 1 , Rugyeom Lee 2 , Kyungmin Huh 3 , Minsun Kang 2 , In Cheol Hwang 4 , Munkhzul Radnaabaatar 2 , Dae Ho Lee 5 , Jaehun Jung 2 6



    AffiliationsFree article

    Abstract

    Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m2; adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m2; aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI ?30 kg/m2) showed similar but non-significant trend. Females and those <50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19.

    Keywords: COVID-19; Infections; Obesity; Overweight.

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