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Clin Immunol . Coronavirus-induced autoimmunity

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  • Clin Immunol . Coronavirus-induced autoimmunity


    Clin Immunol


    . 2021 Feb 18;108694.
    doi: 10.1016/j.clim.2021.108694. Online ahead of print.
    Coronavirus-induced autoimmunity


    Valéry Salle 1



    Affiliations

    Abstract

    The pandemic of Coronavirus disease 2019 (COVID-19), caused by a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spotlighted the link between viral infection and autoimmunity. In this review, we focus on coronavirusinduced autoimmunity based on evidence from experimental animal models, SARSCoV infection with in vitro studies of molecular mimicry and COVID-19 with several clinical reports of autoimmune manifestations of this disease. Further studies will be needed to better characterize the role of SARS-CoV-2 in the development of autoimmunity.

    Keywords: Autoimmunity; COVID-19; Coronavirus.

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