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J Med Virol
. 2021 Feb 9.
doi: 10.1002/jmv.26857. Online ahead of print.
Being pregnant in the COVID-19 pandemic: Effects on the placenta in all aspects
Cemile Merve Seymen 1
Affiliations
- PMID: 33559937
- DOI: 10.1002/jmv.26857
Abstract
The Coronavirus Disease-19 (COVID-19), which spread to the world from Wuhan (China) in late December, was announced as a pandemic by the World Health Organization in March 2020. In addition to acute respiratory syndrome symptoms, this virus also affects non-respiratory organs according to existing data. ACE 2 and TMPRSS2, that play a critical role in the entrance of SARS-COV-2 into the cell, are co-expressed in placental development stages so the placenta also carries a risk for this virus. Many studies have shown that this virus causes some histopathological changes in the placenta. The vertical transmission of the virus is not yet clear, but available data have shown that the indirect effects of the virus can be seen on the fetus. This paper focuses on revealing the effects of the virus on the placenta in all aspects. This article is protected by copyright. All rights reserved.
Keywords: coronavirus; genital tract; pandemics; vertical transmission.