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J Pediatr Hematol Oncol . Pediatric Acute B-Cell Lymphoblastic Leukemia Developing Following Recent SARS-CoV-2 Infection

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  • J Pediatr Hematol Oncol . Pediatric Acute B-Cell Lymphoblastic Leukemia Developing Following Recent SARS-CoV-2 Infection


    J Pediatr Hematol Oncol


    . 2021 Jan 20.
    doi: 10.1097/MPH.0000000000002064. Online ahead of print.
    Pediatric Acute B-Cell Lymphoblastic Leukemia Developing Following Recent SARS-CoV-2 Infection


    Charlotte Leclercq 1 , Fabienne Toutain, Frederic Baleydier, Arnaud G L'Huillier, Noemie Wagner, C?line Lironi, Anne-Marie Calza, Marc Ansari, Geraldine Blanchard-Rohner



    Affiliations

    Abstract

    Coronavirus disease-2019 in children has been linked to various clinical presentation, from paucisymptomatic cutaneous eruptions, to multisystemic inflammatory syndrome. We report the case of an 8-year-old boy who presented with persistent fever and pancytopenia, associated to a skin rash. An extensive etiological workup showed a positive serology for severe acute respiratory syndrome coronavirus 2 and Epstein-Barr virus. A few weeks later, type B acute lymphocytic leukemia was diagnosed. This case underlines the polymorphic appearance of coronavirus disease-2019 and the need for critical appraisal.


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