J Pediatr Hematol Oncol
. 2021 Jan 20.
doi: 10.1097/MPH.0000000000002064. Online ahead of print.
Pediatric Acute B-Cell Lymphoblastic Leukemia Developing Following Recent SARS-CoV-2 Infection
Charlotte Leclercq 1 , Fabienne Toutain, Frederic Baleydier, Arnaud G L'Huillier, Noemie Wagner, C?line Lironi, Anne-Marie Calza, Marc Ansari, Geraldine Blanchard-Rohner
Affiliations
- PMID: 33480653
- DOI: 10.1097/MPH.0000000000002064
Abstract
Coronavirus disease-2019 in children has been linked to various clinical presentation, from paucisymptomatic cutaneous eruptions, to multisystemic inflammatory syndrome. We report the case of an 8-year-old boy who presented with persistent fever and pancytopenia, associated to a skin rash. An extensive etiological workup showed a positive serology for severe acute respiratory syndrome coronavirus 2 and Epstein-Barr virus. A few weeks later, type B acute lymphocytic leukemia was diagnosed. This case underlines the polymorphic appearance of coronavirus disease-2019 and the need for critical appraisal.