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Heart Lung . High incidence and mortality of pneumothorax in critically Ill patients with COVID-19

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  • Heart Lung . High incidence and mortality of pneumothorax in critically Ill patients with COVID-19


    Heart Lung


    . 2020 Oct 14;S0147-9563(20)30397-6.
    doi: 10.1016/j.hrtlng.2020.10.002. Online ahead of print.
    High incidence and mortality of pneumothorax in critically Ill patients with COVID-19


    Xiao-Hui Wang 1 , Jun Duan 1 , Xiaoli Han 1 , Xinzhu Liu 1 , Junhao Zhou 2 , Xue Wang 1 , Linxiao Zhu 1 , Huaming Mou 3 , Shuliang Guo 4



    Affiliations

    Abstract

    Background: The clinical characteristics of the patients with COVID-19 complicated by pneumothorax have not been clarified.
    Objectives: To determine the epidemiology and risks of pneumothorax in the critically ill patients with COVID-19.
    Methods: Retrospectively collecting and analysing medical records, laboratory findings, chest X-ray and CT images of 5 patients complicated by pneumothorax.
    Results: The incidence of pneumothorax was 10% (5/49) in patients with ARDS, 24% (5/21) in patients receiving mechanical ventilation, and 56% (5/9) in patients requiring invasive mechanical ventilation, with 80% (4/5) patients died. All the 5 patients were male and aged ranging from 54 to 79 years old. Pneumothorax was most likely to occur 2 weeks after the beginning of dyspnea and associated with reduction of neuromuscular blockers, recruitment maneuver, severe cough, changes of lung structure and function.
    Conclusions: Pneumothorax is a frequent and fatal complication of critically ill patients with COVID-19.

    Keywords: COVID-19; Coronavirus disease 2019(COVID-19); Epidemiology; Mechanism; Mortality; Pneumothorax; Prevention.

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