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Geriatr Gerontol Int
. 2020 Oct 27.
doi: 10.1111/ggi.14061. Online ahead of print.
Clinical manifestations and factors associated with mortality from COVID-19 in older adults: Retrospective population-based study with 9807 older Brazilian COVID-19 patients
Carlos Df de Souza 1 , Amanda J de Arruda Magalh?es 2 , Ayara Jpd Lima 2 , Danielle N Nunes 2 , ?rika de F?tima Machado Soares 2 , Louryanne de Castro Silva 2 , Lucas G Santos 2 , Vit?ria I Dos Santos Cardoso 2 , Yasmin Vs Nobre 2 , Rodrigo F do Carmo 3 4
Affiliations
- PMID: 33111433
- DOI: 10.1111/ggi.14061
Abstract
Aim: Older adults are the main risk group for coronavirus disease 2019 (COVID-19). This study aimed to describe the clinical manifestations and factors associated with mortality from COVID-19 among older adults in Brazil.
Methods: A cross-sectional observational study was carried out with data from 9807 cases of COVID-19 among older adults in the state of Alagoas, Brazil. We determined the case fatality rate between age groups and clinical factors associated with mortality.
Results: A total of 52.5% (n = 5145) were women, and with an average age of 70.21 ? 8.37 years. The fatality rate was 11.9%, with a higher rate in men (14.4%) compared with women (9.8%). The fatality rate increased with age. The most common manifestations were fever (n = 4926; 50.2%), cough (n = 5737; 58.5%), headache (n = 1980; 20.2%) and fatigue (n = 2022; 20.6%). The most prevalent comorbidities were diabetes (n = 1528; 5.6%), cardiovascular disease (n = 1528; 15.6%) and systemic arterial hypertension (n = 597; 6.1%). The factors associated with mortality were male sex (OR 1.54), age ≥75 years (OR 2.40), dyspnea (OR 2.92), diabetes (OR 2.33), hypertension (OR 1.53) and chronic kidney disease (OR 2.02).
Conclusions: The profile and the risk factors evidenced show the need to adopt mechanisms to protect the elderly population.
Keywords: COVID-19; elderly; geriatric patients; mortality; risk factors.