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J Gastrointest Cancer . Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

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  • J Gastrointest Cancer . Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk


    J Gastrointest Cancer


    . 2020 Oct 1.
    doi: 10.1007/s12029-020-00529-2. Online ahead of print.
    Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk


    Mohammad Hossein Jarahzadeh 1 , Fatemeh Asadian 2 , Meraj Farbod 3 , Bahare Meibodi 4 , Hajar Abbasi 5 , Mohammadali Jafari 6 , Ali Raee-Ezzabadi 6 , Reza Bahrami 7 , Hossein Neamatzadeh 8 9



    Affiliations

    Abstract

    Background: The presence of comorbidity poses a major clinical challenge in the care and treatment of COVID-19 patients. Moreover, having one or more comorbidities could be a life-threatening situation in COVID-19 patients. Cancer is substantially associated with significant morbidity and mortality in COVID-19 patients. However, there is not sufficient data to conclude that cancer patients have a higher risk of COVID-19 infection. In this study, we reviewed cancer comorbidity and risk of mechanical ventilation or death in patients with confirmed COVID-19.
    Methods: A comprehensive systematic search was performed on PubMed, Scopus, Web of Science, SciELO, and CNKI, to find articles published until August 01, 2020. All relevant case series, case reports, systematic and narrative reviews, meta-analyses, and prospective and retrospective studies that reported clinical characteristics and epidemiological information of cancer patients infected with COVID-19 were included in the study.
    Results: A total of 12 cohort studies exclusively on cancer patients with confirmed COVID-19 were selected.
    Conclusions: According to the findings of this study, cancer was not among the most prevalent underlying diseases in patients with confirmed COVID-19. Moreover, cancer patients infected with COVID-19 had the lowest risk of mechanical ventilation or death than the non-cancer infected patients.

    Keywords: COVID-19; Cancer; Death; Intensive care unit; Malignancy; Ventilation.

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