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Neurologia . Smell and taste disorders in Spanish patients with mild COVID-19

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  • Neurologia . Smell and taste disorders in Spanish patients with mild COVID-19


    Neurologia


    . 2020 Jul 28;S0213-4853(20)30233-4.
    doi: 10.1016/j.nrl.2020.07.006. Online ahead of print.
    Smell and taste disorders in Spanish patients with mild COVID-19


    [Article in En, Spanish]

    J Bar?n-S?nchez 1 , C Santiago 2 , G Goizueta-San Mart?n 3 , R Arca 4 , R Fern?ndez 5



    Affiliations

    Abstract

    Introduction: Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the world. Smell and/or taste disorders have emerged as a very frequent symptom as the disease has spread in Europe. Spain is one of the European countries with the highest number of infections.
    Objective: This study aimed to investigate the clinical progression of smell and taste disorders in Spanish patients with mild COVID-19.
    Methods: An online survey was used to conduct a cross-sectional study of patients who presented sudden smell and/or taste disorders during the 2 months of total lockdown due to COVID-19 in Spain.
    Results: In our sample, 91.18% of respondents with impaired smell and/or taste and who were able to undergo PCR testing were positive for SARS-CoV-2 infection. Anosmia and ageusia presented in isolation in 6.5% of participants. The remaining 93.5% presented other mild symptoms: headache (51.6%), cough (51.6%), myalgia (45.2%), asthaenia (38.7%), nasal congestion or rhinorrhoea (35.5%), fever (41.9%), low-grade fever (29.0%), odynophagia (25.8%), or diarrhoea (6.5%). The mean duration of anosmia was 8.33 days, with patients subsequently manifesting hyposmia; complete resolution occurred after a mean of 17.79 days. In 22.6% of respondents, olfactory deficits persisted. All participants recovered their sense of taste.
    Conclusions: Olfactory and gustatory disorders are prevalent symptoms in mild COVID-19. Most patients do not present associated nasal congestion or rhinorrhoea and a small group of patients present these alterations in isolation.

    Keywords: Ageusia; Anosmia; COVID-19; Hiposmia; Hyposmia; Pandemia; Pandemic.

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