Obesity (Silver Spring) . Epicardial Fat Inflammation in severe COVID-19

[tetano]

Obesity (Silver Spring)


. 2020 Aug 30.
doi: 10.1002/oby.23019. Online ahead of print.
Epicardial Fat Inflammation in severe COVID-19


Gianluca Iacobellis ¹ , Francesco Secchi ^{2 3} , Gloria Capitanio ⁴ , Sara Basilico ⁴ , Simone Schiaffino ² , Sara Boveri ⁵ , Francesco Sardanelli ^{2 3} , Massimiliano Marco Corsi Romanelli ^{3 6} , Alexis Elias Malavazos ⁴



Affiliations

• PMID: 32862512
• DOI: 10.1002/oby.23019

Abstract

we read with great interest the paper by Deng et al (1). Obesity increases the risk of coronavirus disease 2019 (COVID-19) morbidity and mortality (2-3). However, Deng et al suggested that not simply obesity, but visceral adiposity is an independent risk factor for COVID-19 complications in young adults (1). Interestingly, visceral fat could serve as reservoir for the virus and amplify the inflammatory response (4-5). Deng et al reported computed tomography (CT) data of ectopic fat depots, such as liver fat and epicardial adipose tissue (EAT), in young COVID-19 patients (1). EAT, the visceral fat depot of the heart, has been suggested to play a role in COVID-19 myocardial inflammation (6-8).