AJNR Am J Neuroradiol
. 2020 Aug 20.
doi: 10.3174/ajnr.A6713. Online ahead of print.
COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum
P Gaur 1 , L Dixon 2 , B Jones 1 , H Lyall 3 , W Jan 1
Affiliations
- PMID: 32819904
- DOI: 10.3174/ajnr.A6713
Abstract
There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.