Open Forum Infect Dis
. 2020 Jun 21;7(7):ofaa249.
doi: 10.1093/ofid/ofaa249. eCollection 2020 Jul.
Coronavirus Disease 2019: Associated Multiple Organ Damage
Olivier Collange 1 , Charles Tacquard 1 , Xavier Delabranche 1 , Ian Leonard-Lorant 2 , Micka?l Ohana 2 , Mihaela Onea 3 , Mathieu Anheim 4 , Morgane Solis 5 , Arnaud Sauer 6 , Seyyid Baloglu 7 , Patrick Pessaux 8 , Patrick Ohlmann 9 , Charlotte Kaeuffer 10 , Walid Oulehri 1 , Stephane Kremer 7 , Paul Michel Mertes 1
Affiliations
- PMID: 32661498
- PMCID: PMC7336548
- DOI: 10.1093/ofid/ofaa249
Abstract
A 56-year-old man presented a particularly severe and multisystemic case of coronavirus disease 2019 (COVID-19). In addition to the common lung and quite common pulmonary embolism and kidney injuries, he presented ocular and intestinal injuries that, to our knowledge, have not been described in COVID-19 patients. Although it is difficult to make pathophysiological hypotheses about a single case, the multiplicity of injured organs argues for a systemic response to pulmonary infection. A better understanding of physiopathology should feed the discussion about therapeutic options in this type of multifocal damage related to severe acute respiratory syndrome coronavirus 2.
Keywords: COVID-19; SARS-CoV-2; brain magnetic resonance imaging; microthrombi; severe acute respiratory syndrome.